Laundry list of crashes in April Update POTCO

[Mythic]

Issues im having, Crashing EVERY SINGLE TIME I MAKE PORT. When using certain potency of tonic(gives 350 hps) weapons would lock up untill I drank another tonic. (any tonic) Unable to access any buildings, caves, graveyards and the like. Upon entering Fort charles recently i would crash, Tested this three times, crashed each time in the hallway.
Someone mentioned a video card issue? Any suggestions on cards that are working well. Im currently using a Radeon 9600 game still runs slow on the least demanding settings.